Hello, I had my liver transplant 2 years ago. Liver function is fine but since the transplant I've had kidney problems (raised urea with symptoms of extreme fatigue). I have monthly iv fluid which brings down the urea and I'm fine again. I have been diagnosed with renal tubular acidosis. Although my doctors are reluctant to connect this to tacrolimus, there is plenty online suggesting a connection.
My transplant doctor has gradually reduced my medication so that I now take just 1mg Prograf morning and 1mg evening. My tacrolimus level is currently 2.7, the doctor is reluctant to reduce the dose any further. He is also reluctant to swop to a different immune-suppressant.
Has anyone else experienced similar side effects while taking tacrolimus (kidney damage)? Does anyone have any suggestions how to deal with this side effect? (I have been prescribed sodium bicarbonate which has helped a little).